He completed a diploma in anaesthetics in East London but being mechanically and technically minded, Dr le Roux's passion for the intricacies of orthopaedics was ignited. In 2010, he began work as an emergency doctor at Life St Dominic's Hospital in East London, and the year thereafter became an orthopaedic senior medical officer at Frere Hospital. After gaining valuable orthopaedic training in East London, Dr le Roux relocated back to Cape Town to serve as a registrar in the orthopaedic surgery department of Stellenbosch University at Tygerberg Hospital and became a Fellow of the College of Surgeons (FC Ortho) in 2019.

After becoming an orthopaedic surgeon, Dr Le Roux went on to pursue subspecialist training by completing a Specialist Knee Surgery Fellowship at Groote Schuur Hospital in 2020. Thereafter he also gained invaluable experience in knee surgery by working part-time with Dr Spike Erasmus at The Stellenbosch Knee Clinic in 2021.

He has authored and co-authored multiple articles in international and local medical journals on topics including cartilage transplantation, knee ligament biomechanics, and the development of a new knee assessment test. He frequently presents these findings at congresses.

Today Dr Le Roux is in private practice as an orthopaedic surgeon performing knee, hip and trauma surgery and remains involved in orthopaedic research.